WebbTarget Information. Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of ... WebbRecombinant human IL-1β is ≥ 95% pure as determined by SDS-PAGE, and an absorbance assay based on the Beers-Lambert law. The endotoxin level is ≤ 1.0 EU per µg of human IL-1β as measured in a chromogenic LAL assay. Brand: BD Pharmingen™ Reactivity: Human (QC Testing) Storage Buffer: Lyophilized in an aqueous buffered solution containing BSA.
Recombinant Human IL-1β - PeproTech
Webb21 dec. 2024 · Objectives: To compare phagocytic activities of monocytes in peripheral blood mononuclear cells (PBMCs) from acute gout patients and normal subjects, examine monosodium urate monohydrate (MSU) crystal-induced IL-1β secretion ± recombinant human proteoglycan 4 (rhPRG4) or interleukin-1 receptor antagonist (IL-1RA), and study … Webb5 nov. 2015 · Addition of recombinant human IL-1β monoclonal antibody or IL-1 receptor antagonist resulted in a dose- and time-dependent protection of cartilage from blood-induced damage. In higher concentrations, almost complete normalization of cartilage matrix proteoglycan turnover was achieved. lighting outlet stores
IL-1b human recombinant, expressed in HEK 293 cells, 95 (SDS …
Webb13 apr. 2024 · IL-1β, IL-6 and TNF-α were purchased from Miltenyi Biotech, IL-23 and TGF-β from R&D Systems, anti-IFN-γ from U-CyTech and anti-IL-4 from BD Pharmingen ... and refreshed every 2 days with IMDM/10% FCS medium containing 10 U/mL recombinant human IL-2 (Novartis AG). After a total culture of 10–12 days, when cells were resting ... WebbTo demonstrate specificity of staining the binding of the Purified Mouse Anti-Human IL-1β (Cat. No. 550007) antibody was blocked by the preincubation of the purified antibody with excess recombinant human IL-1β protein (Cat. No. 554602; data not shown). (Nomarski optics, original magnification 400 X). WebbInterleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 … peak pharmacy chesterfield saltergate