WebJan 31, 1987 · Basis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the full weight-of-evidence narrative. Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 121 K) Oral Slope Factor: 1.4 x 10 -2 per mg/kg-day. WebJan 31, 1987 · Basis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the …
Di (2-ethylhexyl) phthalate-induced toxicity and peroxisome ...
WebTechnical Factsheet on: DI (2-ETHYLHEXYL) PHTHALATE (DEHP) List of Contaminants As part of the Drinking Water and Health pages, this fact sheet is part of a larger … Bis(2-ethylhexyl) phthalate (di-2-ethylhexyl phthalate, diethylhexyl phthalate, diisooctyl phthalate, DEHP; incorrectly — dioctyl phthalate, DIOP) is an organic compound with the formula C6H4(CO2C8H17)2. DEHP is the most common member of the class of phthalates, which are used as plasticizers. It is the … See more Di(2-ethylhexyl) phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para-toluenesulfonic acid. It was first produced … See more DEHP is a component of many household items, including tablecloths, floor tiles, shower curtains, garden hoses, rainwear, dolls, toys, shoes, medical tubing, furniture upholstery, and … See more Taiwan In October 2009, Consumers' Foundation, Taiwan (CFCT) published test results that found 5 out of the sampled 12 shoes contained over … See more • FDA Public Health Notification: PVC devices containing the plasticizer DEHP (archived page) • ATSDR ToxFAQs • CDC - NIOSH Pocket Guide to Chemical Hazards See more Due to its suitable properties and the low cost, DEHP is widely used as a plasticizer in manufacturing of articles made of PVC. Plastics may contain 1% to 40% of DEHP. It is also used as a See more Toxicity The acute toxicity of DEHP is low in animal models: 30 g/kg in rats (oral) and 24 g/kg in rabbits (dermal). Concerns instead focus on its … See more • Maradonna, Francesca; Evangelisti, Matteo; Gioacchini, Giorgia; et al. (2013). "Assay of vtg, ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect … See more rc091v led38s/865 psu w60l60 gm g3
Di(2-Ethylhexyl)Phthalate (DEHP) ToxFAQs™ ATSDR
WebSummary: Di(2-ethylhexyl) phthlate (DEHP) is a manufactured chemical that is commonly added to plastics to make them flexible. DEHP is a colorless liquid with almost no odor. DEHP is a colorless liquid with … WebOct 27, 2024 · High molecular weight phthalates like di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) are commonly used as plasticizers in polyvinyl chloride (PVC) materials such as food ... Web2. Broad agreement: comes from industry data where a majority of data submitters agree the substance is toxic to reproduction. Minority position: comes from industry data where a … rc095v suspending accessory standard